STS-61C was the 24th mission of NASA’s Space Shuttle program, and the seventh mission of Space Shuttle Columbia.
STS-65 marked second flight of International Microgravity Laboratory (IML-2), carrying more than twice the number of experiments and facilities as IML-1. Crew split into two teams to perform around-the-clock research. More than 80 experiments, representing more than 200 scientists from six space agencies, were located in Spacelab module in payload bay (one piece of equipment stowed in middeck lockers). Fifty of the experiments delved into life sciences, including bioprocessing, space biology, human physiology and radiation biology.